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Nanopinion: Graphene oxide reduces the toxicity of misfolded Alzheimer’s proteins

Read the latest Nanopinion by Dr Xin Chen, Prof. Ivan Mijakovic and Dr Santosh Pandit where they discuss the graphene oxide nanoflakes’ interaction with the misfolded Alzheimer’s proteins and their potential to treat neurodegenerative diseases. 

“Alzheimer’s disease is categorized as a protein-misfolding disease. Accumulation of misfolded amyloid-β (Aβ) peptides in the brain is thought to be an early driver of AD, triggering a cascade of pathogenic processes and causing neuronal cell death. Currently, there are only six drugs on the market for the treatment of AD, none of which can stop or reverse the disease progression. This further justifies the urgency for developing alternative strategies against misfolded protein aggregates in AD patients’ brains.”

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